Tighten up your script permissions with this overview
In the interests of information security, it's always important to set up entities and roles with the minimum level of permissions required to get the job done, just as a general principle. To that end, here is the minimal list of permissions you can assign to your ShotGrid systems' "SyncSketch" Script User to fully enable integration with SyncSketch.
More information here if you need help troubleshooting your ShotGrid integration.